In this Webinar the presenter used Page Region to create Thumbnails. Then created Bookmarks from Page Label generated with Page Region in Thumbnails. He then exported the Bookmarks in an index with hyperlinked and used it as a first page in the PDF binder. The problem with that, and you can rewatch the webinar and see the error, is that the hyperlinks are now all offset of 1 page when adding the Page Index at first page.
I also notice that you cannot generate the page index in the Landscape orientation. It just keeps plotting in Portrait